Induction of apoptosis by herpes simplex virus type 1.
نویسندگان
چکیده
Although herpes simplex virus type 1 (HSV-1) does not induce apoptosis in infected HEp-2 cells, in the presence of cycloheximide infection induced apoptosis with characteristic morphological changes as well as endonucleosomal DNA cleavage. The induction of apoptosis without de novo protein synthesis suggests that a structural protein of the HSV-1 virion is responsible for the observed apoptosis.
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ورودعنوان ژورنال:
- The Journal of general virology
دوره 78 ( Pt 11) شماره
صفحات -
تاریخ انتشار 1997